aminoglycosides by thevetscare

Aminoglycosides

aminoglycosides by thevetscare
aminoglycosides by thevetscare

(Gentamicin, Kanamicin, Amikacin, Streptomycin, Neomycin)

Class: Bacteriocidal, Broad Spectrum

Mechansim: Irreversibly bind to the 30S ribosome

Indications: Infections caused by susceptible pathogens, pneuomonias, urinary tract infections, endometritis, and septicemias that are resistant to other antibiotics.

Antagonists: Amphotericin B, Cephalosporins produce nephrotoxicity.

Side effects: Intestinal flora may be disrupted, diarrhea may occur. Other includes intramuscular blockage (when used with anaesthetic agents), nephrotoxicity and ototoxicity (oto=ear)

Notes: These are used in all species

1.  Gentamycin

Horses: 3-6mg/kg BID IM                                Ruminants: 3-6mg/kg BID IM

Trade name Composition Packing Company
Genton 100 mg/ml 50 & 100 ml ICI
Gentasel – 10 100 mg/ml 50 & 100 ml Selmore PH
Medi G 10 100 mg/ml 50 & 100 ml Medivet
Gentasal 100 100 mg/ml 50 & 100 ml Atzan
Gentafar 100 mg/ml 50 & 100 ml Farvet
Gentawan – 10 100 mg/ml 100ml Nawan
Gentalin – 10 100 mg/ml 50,100ml Star
Gentasal – 50 50 mg/ml 100 ml Atzan

2.  Gentamycin + Trimethoprim + Sulfonamide

Trade name Composition Packing Company Recommended Dose
Genta plus 30+125+25 mg/ml 50,100ml Leads Ph. First Dose=30ml/50kg 2nd Dose=15ml/50kg

3. Tylosin + Gentamycin

Trade name Composition Packing Company Recommended Dose
Tylogent 100 + 50 mg/ml 50, 100ml Eterna LA=1ml/30kg SA=1ml/20kg

4. Kanamycin

Notes: More good effects in Dogs & cats. Excessive dose can effect in 8th Cranial Nerve.

Horses: 12-15mg/kg IM                                    Ruminants: 12-15 mg/kg IM

Trade name Composition Packing Company
Kanasym 100 mg/ml 50,100ml Symans
Kanacon 100 mg/ml 50,100ml Vetcon Ph.
Kana Kak 100 mg/ml 50 ml Trust Pharma
Kanamycin 100mg/ml 10, 50ml China
Kanachron 100 mg/ml 10 & 50 ml Star

5.  Kanmycine + Ampicillin + Prednisolone + Chlorpheniramine

Trade name Composition Packing Company Recommended Dose
Kapcine 100mg+200mg+10mg+4mg 50, 100ml Leads Ph. LA=1ml/20kg SA=1ml/10kg

For Pharmacology Watch the following Video

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