
(Gentamicin, Kanamicin, Amikacin, Streptomycin, Neomycin)
Class: Bacteriocidal, Broad Spectrum
Mechansim: Irreversibly bind to the 30S ribosome
Indications: Infections caused by susceptible pathogens, pneuomonias, urinary tract infections, endometritis, and septicemias that are resistant to other antibiotics.
Antagonists: Amphotericin B, Cephalosporins produce nephrotoxicity.
Side effects: Intestinal flora may be disrupted, diarrhea may occur. Other includes intramuscular blockage (when used with anaesthetic agents), nephrotoxicity and ototoxicity (oto=ear)
Notes: These are used in all species
Table of Contents
1. Gentamycin
Horses: 3-6mg/kg BID IM Ruminants: 3-6mg/kg BID IM
Trade name | Composition | Packing | Company |
Genton | 100 mg/ml | 50 & 100 ml | ICI |
Gentasel – 10 | 100 mg/ml | 50 & 100 ml | Selmore PH |
Medi G 10 | 100 mg/ml | 50 & 100 ml | Medivet |
Gentasal 100 | 100 mg/ml | 50 & 100 ml | Atzan |
Gentafar | 100 mg/ml | 50 & 100 ml | Farvet |
Gentawan – 10 | 100 mg/ml | 100ml | Nawan |
Gentalin – 10 | 100 mg/ml | 50,100ml | Star |
Gentasal – 50 | 50 mg/ml | 100 ml | Atzan |
2. Gentamycin + Trimethoprim + Sulfonamide
Trade name | Composition | Packing | Company | Recommended Dose |
Genta plus | 30+125+25 mg/ml | 50,100ml | Leads Ph. | First Dose=30ml/50kg 2nd Dose=15ml/50kg |
3. Tylosin + Gentamycin
Trade name | Composition | Packing | Company | Recommended Dose |
Tylogent | 100 + 50 mg/ml | 50, 100ml | Eterna | LA=1ml/30kg SA=1ml/20kg |
4. Kanamycin
Notes: More good effects in Dogs & cats. Excessive dose can effect in 8th Cranial Nerve.
Horses: 12-15mg/kg IM Ruminants: 12-15 mg/kg IM
Trade name | Composition | Packing | Company |
Kanasym | 100 mg/ml | 50,100ml | Symans |
Kanacon | 100 mg/ml | 50,100ml | Vetcon Ph. |
Kana Kak | 100 mg/ml | 50 ml | Trust Pharma |
Kanamycin | 100mg/ml | 10, 50ml | China |
Kanachron | 100 mg/ml | 10 & 50 ml | Star |
5. Kanmycine + Ampicillin + Prednisolone + Chlorpheniramine
Trade name | Composition | Packing | Company | Recommended Dose |
Kapcine | 100mg+200mg+10mg+4mg | 50, 100ml | Leads Ph. | LA=1ml/20kg SA=1ml/10kg |
For Pharmacology Watch the following Video