Class: Bactericidal, Differ in Generations
Mechanism: Cell wall inhibition
Indications: Very effective for respiratory diseases, Skin diseases and most of bacteria including beta-lactamase producing strains. Also used in Urinary Tract infections, Soft tissues and Bones.
Precaution: Doses should be reduced in liver affected animals. Poorly absorbed from GIT.
Notes: First generation has strongest response against G+ve Cocci, Proteus, E.coli, Klebsiella than other generations. While 3rd Generation has good response against G-ve Bacilli
Narrow Spectrum only for G+ve
|Velosef||250mg/500mg/1gm:||5ml,10ml|| Bristol M.S. |
|Vericef susp.||250mg/500mg/1gm:||60ml,100ml|| Indus |
Horses: 10-30 mg/kg, PO, TID- QID Ruminants: 7mg/kg IM Sid
|Ceporex inj||250mg/500mg||5ml, 10ml||Indus|
|Keflex syp.||25 mg/ ml, 50mg/ ml||60ml||Eli Lilly|
Broad Spectrum both for G+ve and G-ve
1. Ceftiofur Hydochloride
Side effects: Usually safe to use in animals. However allergic reaction can occur. Rare bleeding disorders have been reported from cephalosporins.
Horses: 2.2-5 mg/kg IV IM Ruminants: 1.1-2.2 mg/kg IM IV
|Excenel RTU||50 mg/ml||100 ml||Pfizer|
|Cefur RTU||50 mg/ml||10, 50 & 100 ml||Nawan|
2. Cefotaxime Sodium
Side effects: Usually safe to use in animals. But allergic reactions, vomiting and diarrhea may occur in some animals.
Horses: 20-30 mg/kg IV Ruminants: according to the weight of the animal
|Excef||250mg, 500mg,1gm||5ml, 10ml||Indus|
|Ceforin||250mg,500mg,1gm||10ml, 5ml||Nawan labs|
3. Ceftriaxone Sodium
Horses: 25-50mg/kg IM