(Oxytetracycline, Doxycycline)
Class: Bacteriostatic, Broad Spectrum
Mechanism: Reversibly bind to the 30S ribosome
Indications: Infections caused by tetracycline-sensitive strains; anaplasmosis, often ineffective for endocarditis, empyema, meningitis, septic arthritis and osteomyelitis.
Antagonists: Antacids, milk, diuretics, methoxyflurane, penicillins, ferrous sulfate.
Side effects: Causes nephrotoxicity when administered at high Recommended Doses, Calcium Chelation is the major side effect. Can affect growing bone and teeth formation (cause straining of teeth) in young animals and some hepatotoxicity may occur at large doses.
Notes: Multiple doses should not be given to horses INTRAVENOUSLY. Doxycycline is mostly used in Dogs for Babesiosis.
1. Oxytetracycline (Simple)
Horses: 5mg/Kg IV Ruminants: 5-10mg/kg IM or IV
Foals/Calf= 10-20mg/kg P.O.
| Trade name | Composition | Packing | Company |
| Remoxin | 50 mg/ml | 50 & 100 ml | PDH |
| Oxy S | 50 mg/ml | 50 ml | Selmore PH |
| Nawacin 50 | 50 mg/ml | 50 & 100 ml | Nawan |
| Oxycon – 50 | 50 mg/ml | 50 ml | Vetcon Ph. |
| Resomycin | 50mg/ml | 50ml | Star |
2. Oxytetracycline LA
| Trade name | Composition | Packing | Company | Recommended Dose |
| Oxtra LA | 200 mg/ml | 50 & 100 ml | Fatro | 1 ml/10 kg |
| Oxy LA | 200 mg/ml | 50 & 100 ml | Selmore PH | Same as above |
| Floxitetra LA | 200 mg/ml | 100 ml | Selmore AG | Same as above |
| Nawacin LA | 200 mg/ml | 50 & 100 ml | Nawan | Same as above |
| Remacycline LA | 200 mg/ml | 100 ml | Marush | Same as above |
| Rasomycine LA | 200 mg/ml | 50 ml | Star | Same as above |
3. Oxytetracycline PVD (Poly venyl Pyrolidone)
| Trade name | Composition | Packing | Company | Recommended Dose |
| Oxycare PVP | 100 mg/ml | 50 ml | Vetycare | 1 ml/20 kg |
| Nawacin PVP | 100 mg/ml | 50 & 100 ml | Nawan | 1 ml/20 kg |
| Oxy PVP | 100 mg/ml | 50 & 100 ml | Selmore PH | 1 ml/20 kg |
| Resomycine PVP | 100 mg/ml | 50 ml | Star | 1 ml/20 kg |